Two new phenylpropenoid glycosides from the roots of Illicium dunnianum

Two undescribed phenylpropenoid glycosides (1 − 2) and one known analogues (3) have been isolated and identified from the roots of Illicium dunnianum. The structures of these new compounds were elucidated by extensive spectroscopic analyses (1 D-, 2 D-NMR, HRESIMS, IR, UV) and chemical methods. The...

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Published inNatural product research Vol. 36; no. 21; pp. 5539 - 5544
Main Authors Wang, Yi-lin, Li, Han, Song, Ling, Gao, Yun-hang, Chen, Teng-fei
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 01.11.2022
Taylor & Francis Ltd
Subjects
anti-inflammatory
Glycosides
Illicium
Illicium dunnianum; phenylpropenoid glycosides
Inflammation
Lipopolysaccharides
Macrophages
NMR
Nuclear magnetic resonance
PGE
Prostaglandin E2
Roots
anti-inflammatory
PGE2
Illicium dunnianum; phenylpropenoid glycosides
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Summary:Two undescribed phenylpropenoid glycosides (1 − 2) and one known analogues (3) have been isolated and identified from the roots of Illicium dunnianum. The structures of these new compounds were elucidated by extensive spectroscopic analyses (1 D-, 2 D-NMR, HRESIMS, IR, UV) and chemical methods. The anti-inflammatory activities of all isolates were evaluated by measuring their inhibitory effects on PGE 2 production in LPS stimulated RAW 264.7 macrophages.
Bibliography:ObjectType-Article-1
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content type line 23
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2021.2019736