Three new compounds from Anoectochilus roxburghii (Wall.) Lindl

• Published in: Natural product research Vol. 37; no. 19; pp. 3276 - 3282
• Main Authors: Bin, Yan-Lin, Liu, Shun-Zhi, Xie, Ting-Ting, Feng, Wen-Zheng, Li, Hao-Yang, Ye, Zi-Jia, Dong, Zhi-Hao, Qiu, Ying-Kun
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 02.10.2023; Taylor & Francis Ltd
• Subjects: Anoectochilus roxburghii; Anoectochilus roxburghii (Wall.) Lindl; antioxidant activity; Ethanol; Flavone glycosides; Free radicals; Glycosides; Kaempferol; NMR; Nuclear magnetic resonance; Orchidaceae; Rutin; Scavenging; Anoectochilus roxburghii (Wall.) Lindl; Orchidaceae; antioxidant activity; flavone glycosides
• ISSN: 1478-6419; 1478-6427
• DOI: 10.1080/14786419.2022.2070746

In this study, three new compounds, roxburic acid A (1) and two flavone glycosides isorhamnetin-3-O-α-L-rhamnosyl-(1→6)-β-D-glucopyranose-(1→3)-β-D-glucopyranoside (2), and kaempferol-7-O-β-D-glucopyranosyl-(1→3)-β-D-glucopyranoside (3) were isolated from an ethanol extract of the fresh Anoectochilus roxburghii (Wall.) Lindl., together with 10 known compounds (4-13). The structures of these compounds were comprehensively characterized by HR-ESI-MS, 1 H NMR, 13 C NMR, and 2 D-NMR. The DPPH free radical scavenging activity of the isolated compounds was evaluated, and the results showed that kaempferol-7-O-β-D-glucopyranosyl- (1→3) -β-D-glucopyranoside (3) and rutin (11) has the potential antioxidant activity with IC 50 values of 139 μg/mL and 22.5 μg/mL respectively.