Optimization of media composition for enhancing tetracycline degradation by Trichosporon mycotoxinivorans XPY-10 using response surface methodology

• Published in: Environmental technology Vol. 42; no. 27; pp. 4279 - 4285
• Main Authors: Huang, Xiaochen, Zhang, Xinyang, Huang, Yanyan, Xu, Xuping
• Format: Journal Article
• Language: English; French
• Published: England Taylor & Francis 06.12.2021; Taylor & Francis Ltd
• Subjects: Biodegradation; Box-Behnken design; Empirical analysis; Glucose; Optimization; pH effects; Plackett-Burman design; Response surface methodology; tetracycline; Trichosporon; Biodegradation; Plackett–Burman design; response surface methodology; tetracycline; Box–Behnken design
• ISSN: 0959-3330; 1479-487X
• DOI: 10.1080/09593330.2020.1754472

The objective of the study was to improve tetracycline degradation efficiency by Trichosporon mycotoxinivorans XPY-10 using statistical experimental designs. Different culture conditions (FeSO 4 , pH and glucose) were optimized for tetracycline biodegradation and the mutual interactions between these three variables were analysed using Box-Behnken design (BBD) and response surface methodology (RSM). The results showed that the empirical model was suitable for experimental data, and the maximum tetracycline degradation efficiency by XPY-10 was 95.18% under the optimum conditions of 0.02% of FeSO 4 , pH 7.83 and 0.28% of glucose, which was further verified by experiments. This study indicated the excellent ability of XPY-10 in degrading tetracycline and theoretical support for the follow-up practice to remediate tetracycline contaminated environment.