Recovery of a Multidrug-Resistant Strain of Pandemic Influenza A 2009 (H1N1) Virus Carrying a Dual H275Y/I223R Mutation from a Child after Prolonged Treatment with Oseltamivir

• Published in: Clinical infectious diseases Vol. 51; no. 8; pp. 983 - 984
• Main Authors: Nguyen, Ha T., Fry, Alicia M., Loveless, P. Ann, Klimov, Alexander I., Gubareva, Larisa V.
• Format: Journal Article
• Language: English
• Published: Oxford The University of Chicago Press 15.10.2010; University of Chicago Press; Oxford University Press
• Subjects: Adolescent; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral agents; Antiviral Agents - therapeutic use; Biological and medical sciences; Correspondence; Drug resistance; Drug Resistance, Multiple, Viral; Epidemiology; Female; Genetic mutation; H1N1 subtype influenza A virus; Human viral diseases; Humans; Infectious diseases; Influenza A virus; Influenza A Virus, H1N1 Subtype - drug effects; Influenza A Virus, H1N1 Subtype - genetics; Influenza A Virus, H1N1 Subtype - isolation & purification; Influenza, Human - drug therapy; Influenza, Human - virology; Inhibitory concentration 50; Medical sciences; Mutation, Missense; Nervous system diseases; Neuraminidase - genetics; Oseltamivir - therapeutic use; Pandemics; Pharmacology. Drug treatments; Preventive medicine; Viral diseases; Viral diseases of the respiratory system and ent viral diseases; Viral Proteins - genetics; Viruses; Human; Neuraminidase inhibitor; Enzyme; Respiratory disease; H1N1 influenza; Enzyme inhibitor; Orthomyxoviridae; Glycosylases; Virus; Infection; Oseltamivir; Influenzavirus A; Treatment; Influenza A virus; Exo-α-sialidase; Glycosidases; Viral disease; Multiple resistance; Influenza A (H1N1); Hydrolases; Antiviral; Mutation; Child
• ISSN: 1058-4838; 1537-6591
• DOI: 10.1086/656439