Magnetic Resonance Imaging and Clinical Features of Chlorfenapyr-Induced Toxic Leukoencephalopathy: A Case Report

Chlorfenapyr is widely used as an insecticide, despite it being fatal to humans. However, chlorfenapyr-induced central nervous system toxicity has rarely been reported. We report the magnetic resonance imaging (MRI) findings in a rare case of chlorfenapyr-induced toxic leukoencephalopathy. A 71-year...

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Bibliographic Details
Published inJournal of the Korean Society of Radiology Vol. 81; no. 4; pp. 985 - 989
Main Authors Kim, Jong Hyuk, Park, Noh Hyuck, Park, Ji Yeon, Kim, Seon-Jeong
Format Journal Article
LanguageEnglish
Published The Korean Society of Radiology 01.07.2020
대한영상의학회
Subjects
chlorfenapyr
leukoencephalopathy
magnetic resonance imaging
Neuroradiology & Neurointervention
방사선과학
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ISSN1738-2637
2288-2928
2951-0805
DOI10.3348/jksr.2020.81.4.985

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Summary:Chlorfenapyr is widely used as an insecticide, despite it being fatal to humans. However, chlorfenapyr-induced central nervous system toxicity has rarely been reported. We report the magnetic resonance imaging (MRI) findings in a rare case of chlorfenapyr-induced toxic leukoencephalopathy. A 71-year-old man who had ingested chlorfenapyr approximately two weeks prior visited our hospital and presented with bilateral lower motor weakness and voiding dysfunction that had developed two days before admission. Brain MRI revealed extensive bilateral white matter abnormalities involving the corpus callosum, internal capsule, brain stem, and bilateral middle cerebellar peduncle. Furthermore, spine MRI revealed diffuse swelling and hyperintensity on the T2-weighted images.
Bibliography:https://doi.org/10.3348/jksr.2020.81.4.985
ISSN:1738-2637
2288-2928
2951-0805
DOI:10.3348/jksr.2020.81.4.985