Evaluation and comparison of anti-Candida effect of heat cure polymethylmethacrylate resin enforced with silver nanoparticles and conventional heat cure resins: An in vitro study

Recent years have been dominated by research in nano science. Dentistry is no exception and there is increased research on nanoparticles in dentistry. Complete dentures increase the carriage of Candida in healthy patients, and the proliferation of C. albicans can be associated with denture-induced s...

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Published inIndian journal of dental research Vol. 25; no. 2; pp. 204 - 207
Main Authors Suganya, S, Ahila, S, Kumar, B, Kumar, M
Format Journal Article
LanguageEnglish
Published Mangalore Medknow Publications and Media Pvt. Ltd 01.03.2014
Medknow Publications & Media Pvt. Ltd
Wolters Kluwer Medknow Publications
Subjects
Ag°-silver nanoparticle
Antibiotics
Antimicrobial agents
Bacteria
C. albicans
denture stomatitis
Infections
Medical research
Medicine, Experimental
Microorganisms
Nanoparticles
Nanostructured materials
PMMA-polymethylmethacrylate
Polymethylmethacrylate
Silver
Studies
Toxicity
India
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Summary:Recent years have been dominated by research in nano science. Dentistry is no exception and there is increased research on nanoparticles in dentistry. Complete dentures increase the carriage of Candida in healthy patients, and the proliferation of C. albicans can be associated with denture-induced stomatitis. Purpose: To evaluate the anti-Candida effect of heat cure denture base resins reinforced with Ag in the ratio of 4:1, 3:1, 2:1 (Groups B, C, and D, respectively) to the weight of denture base resins. Materials and Methods: Ag were synthesized by chemical reduction method, incorporated into the polymer powder according to the ratio for each group, subjected to polymerization and microbial assay was calculated for the reference C. albicans strains by agar diffusion method for the incubation period of 24 h. Results: Group D showed multifold decrease in the colony-forming units. Conclusion: The antimicrobial effect of silver could be used vividly in the denture base for immunocompromised and geriatric patients.
ISSN:0970-9290
1998-3603
DOI:10.4103/0970-9290.135923