Serial Magnetic Resonance Imaging Findings in Hyperglycemia-Related Osmotic Demyelination Syndrome: A Case Report

We report a rare case of hyperglycemia-related osmotic demyelination syndrome (ODS) with focus on the imaging findings. A 61-year-old man with diabetes was admitted for general weakness and severe thirst. A few days later, he complained of dysarthria, dysphasia, and dysmetria. Laboratory examination...

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Published inJournal of the Korean Society of Radiology Vol. 81; no. 1; pp. 243 - 247
Main Authors Kim, Jong Hyuk, Park, Noh Hyuck, Park, Ji Yeon, Kim, Seon-Jeong
Format Journal Article
LanguageEnglish
Published The Korean Society of Radiology 2020
대한영상의학회
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ISSN1738-2637
2288-2928
2951-0805
DOI10.3348/jksr.2020.81.1.243

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Abstract We report a rare case of hyperglycemia-related osmotic demyelination syndrome (ODS) with focus on the imaging findings. A 61-year-old man with diabetes was admitted for general weakness and severe thirst. A few days later, he complained of dysarthria, dysphasia, and dysmetria. Laboratory examinations showed significant hyperglycemia, but normal electrolyte levels. Brain MRI revealed T2-signal abnormalities that were symmetrical, non-space occupying, and located in the central pons with a peripheral sparing pattern, which were suggestive of ODS. In addition, subsequent MRI revealed progression of signal hyperintensity; however, the patient's symptoms improved.
AbstractList We report a rare case of hyperglycemia-related osmotic demyelination syndrome (ODS) with focus on the imaging findings. A 61-year-old man with diabetes was admitted for general weakness and severe thirst. A few days later, he complained of dysarthria, dysphasia, and dysmetria. Laboratory examinations showed significant hyperglycemia, but normal electrolyte levels. Brain MRI revealed T2-signal abnormalities that were symmetrical, non-space occupying, and located in the central pons with a peripheral sparing pattern, which were suggestive of ODS. In addition, subsequent MRI revealed progression of signal hyperintensity; however, the patient’s symptoms improved.
We report a rare case of hyperglycemia-related osmotic demyelination syndrome (ODS) with focus on the imaging findings. A 61-year-old man with diabetes was admitted for general weakness and severe thirst. A few days later, he complained of dysarthria, dysphasia, and dysmetria. Laboratory examinations showed significant hyperglycemia, but normal electrolyte levels. Brain MRI revealed T2-signal abnormalities that were symmetrical, non-space occupying, and located in the central pons with a peripheral sparing pattern, which were suggestive of ODS. In addition, subsequent MRI revealed progression of signal hyperintensity; however, the patient’s symptoms improved. KCI Citation Count: 0
Author Kim, Seon-Jeong
Park, Noh Hyuck
Park, Ji Yeon
Kim, Jong Hyuk
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References Rodríguez-Velver (10.3348/jksr.2020.81.1.243_ref8) 2014; 2014
Burns (10.3348/jksr.2020.81.1.243_ref2) 2009; 11
Adams (10.3348/jksr.2020.81.1.243_ref3) 1959; 81
Linyu (10.3348/jksr.2020.81.1.243_ref9) 2017; 16
Hirosawa (10.3348/jksr.2020.81.1.243_ref5) 2018; 85
Chang (10.3348/jksr.2020.81.1.243_ref7) 2014; 2
O'Malley (10.3348/jksr.2020.81.1.243_ref1) 2008; 45
Martin (10.3348/jksr.2020.81.1.243_ref4) 2004; 75 Suppl 3
Saini (10.3348/jksr.2020.81.1.243_ref6) 2015; 56
Osborn (10.3348/jksr.2020.81.1.243_ref10) 2015
References_xml – volume: 11
  start-page: 251
  year: 2009
  ident: 10.3348/jksr.2020.81.1.243_ref2
  publication-title: Neurocrit Care
  doi: 10.1007/s12028-009-9241-9
– volume: 56
  start-page: e71
  year: 2015
  ident: 10.3348/jksr.2020.81.1.243_ref6
  publication-title: Singapore Med J
  doi: 10.11622/smedj.2015065
– volume: 2
  start-page: 1059
  year: 2014
  ident: 10.3348/jksr.2020.81.1.243_ref7
  publication-title: JSM Clin Case Rep
– volume: 85
  start-page: 511
  year: 2018
  ident: 10.3348/jksr.2020.81.1.243_ref5
  publication-title: Cleve Clin J Med
  doi: 10.3949/ccjm.85a.17020
– volume-title: Diagnostic imaging: brain
  year: 2015
  ident: 10.3348/jksr.2020.81.1.243_ref10
– volume: 2014
  start-page: 652523
  year: 2014
  ident: 10.3348/jksr.2020.81.1.243_ref8
  publication-title: Case Rep Neurol Med
– volume: 75 Suppl 3
  start-page: iii22
  year: 2004
  ident: 10.3348/jksr.2020.81.1.243_ref4
  publication-title: J Neurol Neurosurg Psychiatry
– volume: 45
  start-page: 440
  year: 2008
  ident: 10.3348/jksr.2020.81.1.243_ref1
  publication-title: Ann Clin Biochem
  doi: 10.1258/acb.2008.007171
– volume: 81
  start-page: 154
  year: 1959
  ident: 10.3348/jksr.2020.81.1.243_ref3
  publication-title: AMA Arch Neurol Psychiatry
  doi: 10.1001/archneurpsyc.1959.02340140020004
– volume: 16
  start-page: 25
  year: 2017
  ident: 10.3348/jksr.2020.81.1.243_ref9
  publication-title: IOSR-JDMS
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SubjectTerms demyelinating diseases
hyperglycemia
magnetic resonance imaging
Neuroradiology & Neurointervention
방사선과학
Title Serial Magnetic Resonance Imaging Findings in Hyperglycemia-Related Osmotic Demyelination Syndrome: A Case Report
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