Serial Magnetic Resonance Imaging Findings in Hyperglycemia-Related Osmotic Demyelination Syndrome: A Case Report

We report a rare case of hyperglycemia-related osmotic demyelination syndrome (ODS) with focus on the imaging findings. A 61-year-old man with diabetes was admitted for general weakness and severe thirst. A few days later, he complained of dysarthria, dysphasia, and dysmetria. Laboratory examination...

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Published inJournal of the Korean Society of Radiology Vol. 81; no. 1; pp. 243 - 247
Main Authors Kim, Jong Hyuk, Park, Noh Hyuck, Park, Ji Yeon, Kim, Seon-Jeong
Format Journal Article
LanguageEnglish
Published The Korean Society of Radiology 2020
대한영상의학회
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ISSN1738-2637
2288-2928
2951-0805
DOI10.3348/jksr.2020.81.1.243

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Summary:We report a rare case of hyperglycemia-related osmotic demyelination syndrome (ODS) with focus on the imaging findings. A 61-year-old man with diabetes was admitted for general weakness and severe thirst. A few days later, he complained of dysarthria, dysphasia, and dysmetria. Laboratory examinations showed significant hyperglycemia, but normal electrolyte levels. Brain MRI revealed T2-signal abnormalities that were symmetrical, non-space occupying, and located in the central pons with a peripheral sparing pattern, which were suggestive of ODS. In addition, subsequent MRI revealed progression of signal hyperintensity; however, the patient's symptoms improved.
Bibliography:https://doi.org/10.3348/jksr.2020.81.1.243
ISSN:1738-2637
2288-2928
2951-0805
DOI:10.3348/jksr.2020.81.1.243