Letter to the editor: fasting decreases expression of microRNAs linked to endothelial pathophysiology in mononuclear cells of healthy subjects

This study explores how 14–15 h fasting or acute exercise affects immune cell epigenetics, specifically focusing on miRNAs in mononuclear cells. Findings suggest fasting significantly impacts microRNAs associated with endothelial metabolism compared to exercise, but does not directly connect these c...

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Published inApoptosis (London) Vol. 29; no. 7-8; pp. 935 - 937
Main Authors Honeycutt, Denise, Schmidt-Trucksäss, Arno, Brink, Marijke, Kränkel, Nicolle, Kröpfl, Julia M.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.08.2024
Springer
Springer Nature B.V
Subjects
Adult
Apoptosis
Apoptosis - genetics
Autophagy
Autophagy - genetics
Biochemistry
Biomedical and Life Sciences
Biomedicine
Cancer Research
Cell Biology
Endothelial Cells - metabolism
Epigenesis, Genetic
Epigenetics
Exercise - physiology
Fasting
Female
Health promotion
Healthy Volunteers
Humans
Immune system
Leukocytes (mononuclear)
Leukocytes, Mononuclear - metabolism
Male
MicroRNAs - genetics
MicroRNAs - metabolism
miRNA
Oncology
Virology
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Summary:This study explores how 14–15 h fasting or acute exercise affects immune cell epigenetics, specifically focusing on miRNAs in mononuclear cells. Findings suggest fasting significantly impacts microRNAs associated with endothelial metabolism compared to exercise, but does not directly connect these changes to cell apoptosis or autophagy. This enhances comprehension of cellular self-consumption under health-promoting interventions.
Bibliography:SourceType-Scholarly Journals-1
ObjectType-Correspondence-1
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ISSN:1360-8185
1573-675X
1573-675X
DOI:10.1007/s10495-024-01971-4