Effects of Whole-Body Vibration on Prostate Morphology

• Published in: Bulletin of experimental biology and medicine Vol. 146; no. 5; pp. 636 - 641
• Main Authors: Ananev, V. A, Lushnikova, E. L, Abdullaev, N. A, Neymark, A. I
• Format: Journal Article
• Language: English
• Published: Boston Boston : Springer US 01.11.2008; Springer US; Springer Nature B.V
• Subjects: Biomedical and Life Sciences; Biomedicine; Cell Biology; Doppler ultrasonic scanning; Epithelial Cells - pathology; Humans; Internal Medicine; Laboratory Medicine; Male; Microvessels - pathology; Middle Aged; Morphology and Pathomorphology; Myocytes, Smooth Muscle - pathology; Organ Size; Pathology; pathomorphology, ultrastructure; prostate; Prostate - pathology; Ultrasonography, Doppler, Color; Vibration - adverse effects; whole-body vibration; Doppler ultrasonic scanning; prostate; pathomorphology, ultrastructure; whole-body vibration
• ISSN: 0007-4888; 1573-8221
• DOI: 10.1007/s10517-009-0362-0

The peculiarities of the prostate remodeling caused by long-term whole-body vibration were investigated. Vibrational prostatopathy was characterized by more incident and pronounced decrease in prostate size, blurred contours, and appearance of sites with changed density (fibrosis, calcification, cysts) in central and peripheral zones of the gland. Vibrogenic prostate remodeling is determined by marked reduction of microvessel and prostatic glands, particularly in the central (periurethral) part, smooth muscle cell hyperplasia and hypertrophy, and marked fibrosis of the stroma in the absence of inflammatory cellular infiltration. Morphological data describing reduction of microvessels in the prostate caused by whole-body vibration correlate with Doppler scanning data indicating reduced perfusion of the organ.