Preprocedural plasma C-reactive protein levels, postprocedural creatine kinase-MB release, and long-term prognosis after successful coronary stenting (four-year results from the GENERATION study)

• Published in: The American journal of cardiology Vol. 95; no. 3; pp. 386 - 390
• Main Authors: Zairis, Michael N., Ambrose, John A., Ampartzidou, Olga, Lyras, Anastassios G., Manousakis, Stavros J., Makrygiannis, Stamatis S., Beldekos, Demetrios J., Devoe, Mary C., Fakiolas, Constantine N., Prekates, Athanasios A., Olympios, Christopher D., Argyrakis, Spyros K., Foussas, Stefanos G.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.02.2005; Elsevier
• Subjects: Aged; Biological and medical sciences; C-Reactive Protein - metabolism; Cardiology. Vascular system; Chi-Square Distribution; Coronary Disease - blood; Coronary Disease - therapy; Coronary heart disease; Creatine Kinase - metabolism; Creatine Kinase, MB Form; Female; Heart; Humans; Isoenzymes - metabolism; Male; Medical sciences; Middle Aged; Predictive Value of Tests; Prognosis; Prospective Studies; Regression Analysis; Statistics, Nonparametric; Stents; Creatine kinase MB; Protein kinase C; Prognosis; Enzyme; Transferases; Coronary artery; Instrumentation therapy; Cardiovascular disease; Coronary heart disease; Long term; Stent; Blood plasma; Generation; Level; C reactive protein; Release
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2004.09.039

Increased creatine kinase-MB isoenzymes after coronary stenting are common, and many studies have suggested an association of this increase with an adverse long-term prognosis. How such postprocedural creatine kinase-MB release affects long-term prognosis remains unclear. Whether any actual causal relation exists remains unanswered.