Revealing anti-inflammatory mechanisms of soy isoflavones by flow: modulation of leukocyte-endothelial cell interactions

• Published in: American journal of physiology. Heart and circulatory physiology Vol. 289; no. 2; pp. H908 - H915
• Main Authors: Chacko, Balu K, Chandler, Robert T, Mundhekar, Ameya, Khoo, Nicholas, Pruitt, Heather M, Kucik, Dennis F, Parks, Dale A, Kevil, Christopher G, Barnes, Stephen, Patel, Rakesh P
• Format: Journal Article
• Language: English
• Published: United States 01.08.2005
• Subjects: Anti-Inflammatory Agents - pharmacology; Aorta; Cell Adhesion - drug effects; Cell Adhesion Molecules - metabolism; Cell Communication - drug effects; Cells, Cultured; Endothelial Cells - physiology; Genistein - pharmacology; Glycine max - chemistry; Humans; Isoflavones - pharmacology; Leukocytes - physiology; Monocytes - physiology; Phosphorylation; PPAR gamma - physiology; Reactive Oxygen Species - metabolism; Receptors, Estrogen - metabolism; Stress, Mechanical; Tumor Necrosis Factor-alpha - pharmacology; Tyrosine - metabolism

Departments of 1 Pathology, 2 Pharmacology, and 3 Anesthesiology, 4 Purdue-University of Alabama at Birmingham Botanical Center for Age-Related Disease, and 5 Center for Free Radical Biology, University of Alabama at Birmingham; and 6 Research Service, Birmingham Veterans Affairs Medical Center, Bir...