Intraoperative pulmonary hyperdistention estimated by transthoracic lung ultrasound: A pilot study

• Published in: Anaesthesia critical care & pain medicine Vol. 39; no. 6; pp. 825 - 831
• Main Authors: Tonelotto, Bruno, Pereira, Sérgio Martins, Tucci, Mauro Roberto, Vaz, Diogo Florenzano, Vieira, Joaquim Edson, Malbouisson, Luiz Marcelo, Gay, Frédérick, Simões, Claudia Marquez, Carvalho Carmona, Maria José, Monsel, Antoine, Amato, Marcelo Brito, Rouby, Jean-Jacques, Costa Auler, José Otavio
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01.12.2020
• Subjects: A lines; Humans; Impedance tomography; Lung - diagnostic imaging; Lung ultrasound; Pilot Projects; Positive end-expiratory pressure; Positive-Pressure Respiration; Pulmonary Atelectasis - diagnostic imaging; Pulmonary hyperdistention; Recruitment manoeuvre; Respiration, Artificial; Impedance tomography; PEEP; ROC; ICC; LU; Positive end-expiratory pressure; Lung ultrasound; Recruitment manoeuvre; CT; EIT; A lines; Pulmonary hyperdistention; BMI
• ISSN: 2352-5568; 2352-5568
• DOI: 10.1016/j.accpm.2020.09.009

Transthoracic lung ultrasound can assess atelectasis reversal and is considered as unable to detect associated hyperdistention. In this study, we describe an ultrasound pattern highly suggestive of pulmonary hyperdistention. Eighteen patients with normal lungs undergoing lower abdominal surgery were studied. Electrical impedance tomography was calibrated, followed by anaesthetic induction, intubation and mechanical ventilation. To reverse posterior atelectasis, a recruitment manoeuvre was performed. Positive-end expiratory pressure (PEEP) titration was then obtained during a descending trial – 20, 18, 16, 14, 12, 10, 8, 6 and 4cmH2O. Ultrasound and electrical impedance tomography data were collected at each PEEP level and interpreted by two independent observers. Spearman correlation test and receiving operating characteristic curve were used to compare lung ultrasound and electrical impedance tomography data. The number of horizontal A lines increased linearly with PEEP: from 3 (0, 5) at PEEP 4cmH2O to 10 (8, 13) at PEEP 20cmH2O. The increase number of A lines was associated with a parallel and significant decrease in intercostal space thickness (p=0.001). The lung ultrasound threshold for detecting pulmonary hyperdistention was defined as the number of A lines counted at the PEEP preceding the PEEP providing the best respiratory compliance. Six A lines was the median threshold for detecting pulmonary hyperdistention. The area under the receiving operating characteristic curve was 0.947. Intraoperative transthoracic lung ultrasound can detect lung hyperdistention during a PEEP descending trial. Six or more A lines detected in normally aerated regions can be considered as indicating lung hyperdistention. Trial registration: NCT02314845 Registered on ClinicalTrials.gov.