Proton magnetic resonance spectroscopy of the kidney in renal stone disease

• Published in: Magnetic resonance imaging Vol. 20; no. 10; pp. 777 - 779
• Main Authors: Mairiang, Eimorn, Hanpanich, Petcharakorn, Sriboonlue, Pote
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.12.2002; Elsevier Science
• Subjects: Biological and medical sciences; Humans; Investigative techniques, diagnostic techniques (general aspects); Kidney; Kidney - chemistry; Kidney Calculi - diagnosis; Kidney Calculi - metabolism; Magnetic Resonance Spectroscopy; Medical sciences; Osmolar Concentration; Osmolytes; Proton MR spectroscopy; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Renal stone disease; Tropical medicine; Urinary system; Thailand; Asia; Renal stone disease; Kidney; Osmolytes; Proton MR spectroscopy; Kidney disease; Human; Urinary system disease; NMR spectrometry; Urinary stone; Lithiasis; Proton; Medical imagery; Diagnosis; Comparative study
• ISSN: 0730-725X; 1873-5894
• DOI: 10.1016/S0730-725X(02)00622-7

Previous studies of renal stone disease (RSD) in Thailand indicated abnormal urinary aggregator and inhibitor composition among farmers with excessive sweat loss. Our aim was to compare the proton MR spectra obtained from the kidneys of 32 proven cases of RSD (aged 38 to 65 yrs) with nine age-matched normal control subjects. We used the STEAM sequence with TE = 15 ms and TR = 2000 ms. The spectra at 3.25, 3.6 and 3.9 ppm were analyzed. The results showed a correlation between the three peaks ( p < 0.001), however, there was no significant difference between the RSD group and the normal control subjects. We therefore concluded that there was no overloading of these osmolytes among the renal stone patients.