Identifying Barriers to Medication Adherence in Adolescent Transplant Recipients

Objective To create Parent and Adolescent Medication Barriers Scales (PMBS and AMBS) for assessing perceived barriers to medication adherence in adolescent transplant recipients. Methods These scales were developed and initially validated with 78 families. Participants responded to questions concern...

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Bibliographic Details
Published inJournal of pediatric psychology Vol. 32; no. 7; pp. 831 - 844
Main Authors Simons, Laura E., Blount, Ronald L.
Format Journal Article
LanguageEnglish
Published Atlanta, GA Oxford University Press 01.08.2007
Subjects
Adolescent
Attitude to Health
Biological and medical sciences
Child clinical studies
Demography
Drug Therapy - statistics & numerical data
Drug-Related Side Effects and Adverse Reactions
Female
Humans
Male
Medical sciences
Organ Transplantation - statistics & numerical data
Patient Compliance - statistics & numerical data
Psychology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Surveys and Questionnaires
pediatric transplant
adolescent
medication
adherence
measurement
Human
Pediatrics
Transplantation
Adhesion
Drug compliance
Chemotherapy
Treatment
Surgery
Adolescent
Graft
Child
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Summary:Objective To create Parent and Adolescent Medication Barriers Scales (PMBS and AMBS) for assessing perceived barriers to medication adherence in adolescent transplant recipients. Methods These scales were developed and initially validated with 78 families. Participants responded to questions concerning perceived barriers to medication adherence. To assess validity, data on contextual factors (e.g., family functioning) and adherence measures were collected. Results A principal components factor analysis resulted in the following subscales for the PMBS and AMBS: (a) Disease Frustration/Adolescent Issues, (b) Regimen Adaptation/Cognitive Issues, (c) Ingestion Issues, and (d) Parent Reminder (PMBS only). Significant associations were found between barrier scale scores, contextual factors, and adherence. Conclusions The PMBS and AMBS are brief and psychometrically promising scales for assessing perceived barriers to adherence in adolescent transplant recipients.
ISSN:0146-8693
1465-735X
DOI:10.1093/jpepsy/jsm030