Pyomyositis as a focus of infection in hematological disorders: A report of 3 cases

• Published in: International journal of hematology Vol. 77; no. 2; pp. 171 - 174
• Main Authors: HAYASHI, Tatsuyuki, NOZAKI, Miho, NONAKA, Yasunobu, OHASHI, Kazuteru, SAKAMAKI, Hisashi, NOMURA, Takeo
• Format: Journal Article
• Language: English
• Published: Tokyo Springer 01.02.2003; Springer Nature B.V
• Subjects: Adult; Aged; Biological and medical sciences; Drug Resistance, Bacterial; Fatal Outcome; Hematologic and hematopoietic diseases; Hematologic Diseases - complications; Hematologic Diseases - drug therapy; Humans; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis; Magnetic Resonance Imaging; Male; Medical sciences; Methicillin; Middle Aged; Myositis - diagnosis; Myositis - drug therapy; Myositis - etiology; Neutropenia; Opportunistic Infections - diagnosis; Opportunistic Infections - drug therapy; Staphylococcal Infections - diagnosis; Staphylococcal Infections - drug therapy; Staphylococcal Infections - etiology; Staphylococcus aureus; Human; Opportunistic infection; Male; Malignant hemopathy; Nuclear magnetic resonance imaging; Infection; Case study; Striated muscle disease; Magnetic resonance imaging; Methicillin-resistant Staphylococcus aureus; Pyomyositis; Bacteriosis; Bacteria; Medical imagery; Micrococcales; Complication; Myositis; Micrococcaceae; Diagnosis; Hematological disorders; Staphylococcus aureus
• ISSN: 0925-5710; 1865-3774
• DOI: 10.1007/BF02983216

The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous leukemia and 2 men aged 46 and 71 years with neutropenia due to myelodysplastic syndromes all reported high fever and severe local myalgia and had marked elevation of C-reactive protein. Magnetic resonance imaging revealed muscle abscesses or fasciitis, and the findings led to the diagnosis of pyomyositis. Methicillin-resistant Staphylococcus aureus was isolated from the abscesses of 2 patients, and surgical drainage proved more effective than did antimicrobial agents. It should be recognized that pyomyositis is a possible source of infection in patients with hematological disorders.