Biomonitoring of 29 trace elements in whole blood from inhabitants of Cotonou (Benin) by ICP-MS

• Published in: Journal of trace elements in medicine and biology Vol. 43; pp. 38 - 45
• Main Authors: Yedomon, Brice, Menudier, Alain, Etangs, Florence Lecavelier Des, Anani, Ludovic, Fayomi, Benjamin, Druet-Cabanac, Michel, Moesch, Christian
• Format: Journal Article
• Language: English
• Published: Germany Elsevier GmbH 01.09.2017; Elsevier
• Subjects: Adolescent; Adult; Benin; Biomonitoring; Blood donors; Environmental Monitoring; Environmental Monitoring - methods; Europe; Female; Humans; ICP-MS; Life Sciences; Male; Mass Spectrometry; Mass Spectrometry - methods; Santé publique et épidémiologie; Trace Elements; Trace Elements - blood; Whole blood; Young Adult; Whole blood; Benin; Biomonitoring; Trace elements; ICP-MS; Blood donors
• ISSN: 0946-672X; 1878-3252
• DOI: 10.1016/j.jtemb.2016.11.004

This study aimed to investigate the blood concentration of 29 trace elements, metals or metalloids, in a healthy population of Cotonou not directly exposed to metals in order to propose reference values. Blood samples from 70 blood donors were collected in K2 EDTA tubes for trace elements during September 2015 and a questionnaire was used to assess lifestyle exposure. Blood metal concentrations were determined by inductively coupled plasma mass spectrometry (ICP-MS) equipped with a quadrupole-based reaction cell. Among the selected blood donors 51.4% were aged from 18 to 36 years and 49.6% from 37 to 65 years. Among the 29 elements analyzed As, Pb, Mn, Pd, Sb, Co, Se, Sr showed blood concentrations higher than the reference values found in the literature for non-exposed healthy European populations and their geometric means were respectively 5.81; 47.39; 19.71; 1.91; 7.50; 0.66; 163.01; 30.53μg/L. This study provides the first reference value (5th–95th percentiles) for each element in Cotonou, which enables us to carry out further investigations on environmental and occupational exposure.