Mandibular metastasis of papillary thyroid carcinoma: a case report and systematic literature review

In this paper, we systematically review the literature on papillary thyroid carcinoma (PTC) metastasis to the mandible. This is a rare oc-currence, especially in young, asymptomatic patients. We propose appropriate surgical and adjuvant therapy guidelines based on our findings. A systematic PubMed s...

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Published inJournal of the Korean Association of Oral and Maxillofacial Surgeons Vol. 51; no. 2; pp. 73 - 79
Main Authors Shin, Yootaek, Kim, Hyounmin, Yang, Solbin, Han, Seung-Yong, Cho, Eunae Sandra, Kim, Dongwook, Kim, Hyung Jun
Format Journal Article
LanguageEnglish
Published Korea (South) The Korean Association of Oral and Maxillofacial Surgeons 30.04.2025
대한구강악안면외과학회
Subjects
Review
치의학
Mandible
Papillary carcinoma
Neoplasm metastasis
Thyroid neoplasm
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Summary:In this paper, we systematically review the literature on papillary thyroid carcinoma (PTC) metastasis to the mandible. This is a rare oc-currence, especially in young, asymptomatic patients. We propose appropriate surgical and adjuvant therapy guidelines based on our findings. A systematic PubMed search (up to July 2023) identified 10 eligible cases of papillary or follicular thyroid carcinoma with metastasis to the mandible. Studies of patients with different histologic types or without confirmed distant metastasis were excluded. A rare case of PTC metastasizing to the mandible in a young male highlights an unusual presentation. Surgical treatment of both primary and metastatic sites, along with aggressive adjuvant therapy after surgery, had a positive impact on survival.
Bibliography:ObjectType-Article-1
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ISSN:2234-7550
2234-5930
DOI:10.5125/jkaoms.2025.51.2.73