Neonatal Diagnostics: Toward Dynamic Growth Charts of Neuromotor Control
The current rise of neurodevelopmental disorders poses a critical need to detect risk early in order to rapidly intervene. One of the tools pediatricians use to track development is the standard growth chart. The growth charts are somewhat limited in predicting possible neurodevelopmental issues. Th...
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Published in | Frontiers in pediatrics Vol. 4; p. 121 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Switzerland
Frontiers Media S.A
23.11.2016
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Subjects | |
Online Access | Get full text |
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Summary: | The current rise of neurodevelopmental disorders poses a critical need to detect risk early in order to rapidly intervene. One of the tools pediatricians use to track development is the standard growth chart. The growth charts are somewhat limited in predicting possible neurodevelopmental issues. They rely on linear models and assumptions of normality for physical growth data - obscuring key statistical information about possible neurodevelopmental risk in growth data that actually has accelerated, non-linear rates-of-change and variability encompassing skewed distributions. Here, we use new analytics to profile growth data from 36 newborn babies that were tracked longitudinally for 5 months. By switching to incremental (velocity-based) growth charts and combining these dynamic changes with underlying fluctuations in motor performance - as the transition from spontaneous random noise to a systematic signal - we demonstrate a method to detect very early stunting in the development of voluntary neuromotor control and to flag risk of neurodevelopmental derail. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Edited by: Gerry Leisman, The National Institute of Brain & Rehabilitation Sciences, Israel; Universidad de Ciencias Médicas de la Habana, Cuba Reviewed by: Marcelo Fernandes Costa, University of São Paulo, Brazil; Daniel Rossignol, Rossignol Medical Center, USA Specialty section: This article was submitted to Child Health and Human Development, a section of the journal Frontiers in Pediatrics |
ISSN: | 2296-2360 2296-2360 |
DOI: | 10.3389/fped.2016.00121 |