Enhanced specific antibody response to bovine serum albumin in pigeons due to L-carnitine supplementation

• Published in: British poultry science Vol. 41; no. 4; pp. 448 - 453
• Main Authors: Janssens, G.P.J., Mast, J., Goddeeris, B.M., Cox, E., Hesta, M., De Wilde, R.O.M.
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis Group 01.09.2000; Taylor & Francis Ltd
• Subjects: Animals; Body Weight; Carnitine - administration & dosage; Carnitine - immunology; Columbidae - immunology; Enzyme-Linked Immunosorbent Assay - veterinary; Female; Immunoglobulin G - biosynthesis; Immunoglobulin G - blood; Immunoglobulin M - biosynthesis; Immunoglobulin M - blood; Linear Models; Random Allocation; Serum Albumin, Bovine - immunology
• ISSN: 0007-1668; 1466-1799
• DOI: 10.1080/713654972

1. Thirty adult female pigeons (Columba livia domestica) were randomly divided into 3 equal groups; the 1st and 2nd groups were immunised with bovine serum albumin (BSA) at 0 and 20 d, the 2nd group also received 1 g L-carnitine per litre of drinking water from -5 to 25 d post-immunisation (dpi) and the 3rd group, a control group, received neither treatment. 2. Body weights and serum samples were taken at 0, 5, 10, 15, 20, 25, 30 and 35 dpi. 3. Both BSA-specific IgG and IgM responses were enhanced by about 10% by L-carnitine supplementation. 4. L-carnitine supplemented pigeons showed a higher water consumption. Body weight loss during the onset of the immune response showed a slight tendency to be counteracted by L-carnitine supplementation. 5. The impact of L-carnitine on resistance and resilience to an immunological challenge is discussed.