Reference-grade Taxus genome unleashes its pharmacological potential

The genus Taxus is well known for its anticancer metabolite, paclitaxel. Recent releases of chromosome-scale reference genomes for two Taxus species (Xiong et al. and Cheng et al.) now provide novel insights on genome structure and phylogenomics and the origin and evolution of the paclitaxel biosynt...

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Bibliographic Details
Published inTrends in plant science Vol. 27; no. 1; pp. 10 - 12
Main Authors Kui, Ling, Majeed, Aasim, Dong, Yang
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.01.2022
Elsevier BV
Subjects
Biosynthesis
Chromosomes
genome
Genomes
Metabolites
Paclitaxel
Phylogeny
taxadiene synthase
Taxus
Taxus - genetics
WGD
genome
paclitaxel
taxadiene synthase
Taxus
WGD
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Summary:The genus Taxus is well known for its anticancer metabolite, paclitaxel. Recent releases of chromosome-scale reference genomes for two Taxus species (Xiong et al. and Cheng et al.) now provide novel insights on genome structure and phylogenomics and the origin and evolution of the paclitaxel biosynthesis pathway.
Bibliography:ObjectType-Article-2
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ISSN:1360-1385
1878-4372
DOI:10.1016/j.tplants.2021.10.010