Ion-pair chromatography of acidic drug metabolites and endogenic compounds

• Published in: Journal of chromatography Vol. 125; no. 1; p. 327
• Main Authors: Fransson, B, Wahlund, K G, Johansson, I M, Schill, G
• Format: Journal Article
• Language: English
• Published: Netherlands 29.09.1976
• Subjects: Barbiturates - analysis; Biogenic Amines - analysis; Carboxylic Acids - analysis; Chromatography, Ion Exchange; Glucuronates - analysis; Glycine - analysis; Hydrogen-Ion Concentration; Methods; Pharmaceutical Preparations; Phenols - analysis; Solvents; Steroids - analysis; Sulfonamides - analysis; Sulfuric Acids - analysis

Liquid-liquid chromatographic systems based on ion-pair partition with silica microparticles as the support for the stationary phase have been used for the separation of anionic compounds of biochemical and pharmacological interest. A high separating efficiency can be obtained with both aqueous and...