Unruptured intracranial aneurysms: seizures and antiepileptic drug treatment following surgery

Twenty-one patients operated on for unruptured intracranial aneurysms were studied retrospectively in order to identify the incidence of postoperative seizures, factors predictive of seizures, and the response to discontinuation of antiepileptic drugs. The overall risk of postoperative seizures in i...

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Bibliographic Details
Published inJournal of neurosurgery Vol. 75; no. 3; p. 371
Main Authors Rabinowicz, A L, Ginsburg, D L, DeGiorgio, C M, Gott, P S, Giannotta, S L
Format Journal Article
LanguageEnglish
Published United States 01.09.1991
Subjects
Anticonvulsants - therapeutic use
Follow-Up Studies
Humans
Incidence
Intracranial Aneurysm - complications
Intracranial Aneurysm - surgery
Postoperative Complications - epidemiology
Postoperative Complications - prevention & control
Retrospective Studies
Risk Factors
Seizures - epidemiology
Seizures - etiology
Seizures - prevention & control
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Summary:Twenty-one patients operated on for unruptured intracranial aneurysms were studied retrospectively in order to identify the incidence of postoperative seizures, factors predictive of seizures, and the response to discontinuation of antiepileptic drugs. The overall risk of postoperative seizures in initially seizure-free patients was 15.7%. Although seizures were not uncommon, antiepileptic drugs were successfully tapered in most of the patients before 12 months.
ISSN:0022-3085
DOI:10.3171/jns.1991.75.3.0371