Intracavity wavelength modulation of an optical parametric oscillator for coherent Raman microscopy

We present a novel intracavity frequency modulation scheme in a tunable, picosecond optical parametric oscillator (OPO). The OPO signal wavelength can be modulated with a depth of more than 10 nm at a rate of 38 MHz (one half its repetition rate). We discuss the design and construction of the light...

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Published inOptics express Vol. 17; no. 15; pp. 12532 - 12539
Main Authors Saar, Brian G, Holtom, Gary R, Freudiger, Christian W, Ackermann, Chrisita, Hill, Winfield, Xie, X Sunney
Format Journal Article
LanguageEnglish
Published United States 20.07.2009
Subjects
Animals
Equipment Design
Hair
Lasers
Light
Mice
Microscopy - methods
Minoxidil - pharmacology
Optics and Photonics
Oscillometry - methods
Physics - methods
Scattering, Radiation
Skin - pathology
Spectrum Analysis, Raman - methods
Time Factors
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Abstract We present a novel intracavity frequency modulation scheme in a tunable, picosecond optical parametric oscillator (OPO). The OPO signal wavelength can be modulated with a depth of more than 10 nm at a rate of 38 MHz (one half its repetition rate). We discuss the design and construction of the light source and its application to the recently-developed frequency modulation coherent anti-Stokes Raman scattering (FM-CARS) and stimulated Raman scattering (SRS) techniques. The new light source allows for real time subtraction of the interfering background signal in coherent Raman imaging, yielding images with purely chemical contrast.
AbstractList We present a novel intracavity frequency modulation scheme in a tunable, picosecond optical parametric oscillator (OPO). The OPO signal wavelength can be modulated with a depth of more than 10 nm at a rate of 38 MHz (one half its repetition rate). We discuss the design and construction of the light source and its application to the recently-developed frequency modulation coherent anti-Stokes Raman scattering (FM-CARS) and stimulated Raman scattering (SRS) techniques. The new light source allows for real time subtraction of the interfering background signal in coherent Raman imaging, yielding images with purely chemical contrast.
Author Saar, Brian G
Hill, Winfield
Xie, X Sunney
Holtom, Gary R
Ackermann, Chrisita
Freudiger, Christian W
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Snippet We present a novel intracavity frequency modulation scheme in a tunable, picosecond optical parametric oscillator (OPO). The OPO signal wavelength can be...
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SubjectTerms Animals
Equipment Design
Hair
Lasers
Light
Mice
Microscopy - methods
Minoxidil - pharmacology
Optics and Photonics
Oscillometry - methods
Physics - methods
Scattering, Radiation
Skin - pathology
Spectrum Analysis, Raman - methods
Time Factors
Title Intracavity wavelength modulation of an optical parametric oscillator for coherent Raman microscopy
URI https://www.ncbi.nlm.nih.gov/pubmed/19654655
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