Intracavity wavelength modulation of an optical parametric oscillator for coherent Raman microscopy

We present a novel intracavity frequency modulation scheme in a tunable, picosecond optical parametric oscillator (OPO). The OPO signal wavelength can be modulated with a depth of more than 10 nm at a rate of 38 MHz (one half its repetition rate). We discuss the design and construction of the light...

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Bibliographic Details
Published inOptics express Vol. 17; no. 15; pp. 12532 - 12539
Main Authors Saar, Brian G, Holtom, Gary R, Freudiger, Christian W, Ackermann, Chrisita, Hill, Winfield, Xie, X Sunney
Format Journal Article
LanguageEnglish
Published United States 20.07.2009
Subjects
Animals
Equipment Design
Hair
Lasers
Light
Mice
Microscopy - methods
Minoxidil - pharmacology
Optics and Photonics
Oscillometry - methods
Physics - methods
Scattering, Radiation
Skin - pathology
Spectrum Analysis, Raman - methods
Time Factors
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Summary:We present a novel intracavity frequency modulation scheme in a tunable, picosecond optical parametric oscillator (OPO). The OPO signal wavelength can be modulated with a depth of more than 10 nm at a rate of 38 MHz (one half its repetition rate). We discuss the design and construction of the light source and its application to the recently-developed frequency modulation coherent anti-Stokes Raman scattering (FM-CARS) and stimulated Raman scattering (SRS) techniques. The new light source allows for real time subtraction of the interfering background signal in coherent Raman imaging, yielding images with purely chemical contrast.
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ISSN:1094-4087
1094-4087
DOI:10.1364/oe.17.012532