Toward the potential cure of leukemias in the next decade

Historically, progress in leukemia research has been slow, but it has accelerated recently as a result of understanding the pathophysiology of leukemias and implementing more effective and targeted therapies. This review summarizes the progress across leukemia subsets and projects the potential cure...

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Bibliographic Details
Published inCancer Vol. 124; no. 22; pp. 4301 - 4313
Main Authors Kantarjian, Hagop M., Keating, Michael J., Freireich, Emil J
Format Journal Article
LanguageEnglish
Published United States Wiley Subscription Services, Inc 15.11.2018
Subjects
Antineoplastic Agents - therapeutic use
cure
Disease-Free Survival
Historical account
Humans
Leukemia
Leukemia - classification
Leukemia - genetics
Leukemia - therapy
leukemias
Oncology
Standard of Care
Stem Cell Transplantation
targeted
therapy
Treatment Outcome
treatments
targeted
leukemias
cure
therapy
treatments
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Summary:Historically, progress in leukemia research has been slow, but it has accelerated recently as a result of understanding the pathophysiology of leukemias and implementing more effective and targeted therapies. This review summarizes the progress across leukemia subsets and projects the potential cure of most leukemias in the next decade. This review summarizes the major progress toward the curing all leukemias in the foreseeable future. The therapeutic tools necessary to cure most, if not all, leukemias within the next decade already may be available, and these need to be investigated in combination with both established treatments and other investigational agents in well designed regimens to define new standard‐of‐care curative regimens across all leukemias.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0008-543X
1097-0142
DOI:10.1002/cncr.31669