Potential diagnostic biomarkers for schizophrenia

Abstract Schizophrenia (SCH) is a complex and severe mental disorder with high prevalence, disability, mortality and carries a heavy disease burden, the lifetime prevalence of SCH is around 0.7%–1.0%, which has a profound impact on the individual and society. In the clinical practice of SCH, key pro...

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Bibliographic Details
Published inMedical Review Vol. 2; no. 4; pp. 385 - 416
Main Authors Yue, Weihua, Huang, Hailiang, Duan, Jubao
Format Journal Article
LanguageEnglish
Published De Gruyter 01.08.2022
Subjects
accurate diagnosis
multi-omics data
objective biomarkers
personalized treatment
Review
schizophrenia
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Summary:Abstract Schizophrenia (SCH) is a complex and severe mental disorder with high prevalence, disability, mortality and carries a heavy disease burden, the lifetime prevalence of SCH is around 0.7%–1.0%, which has a profound impact on the individual and society. In the clinical practice of SCH, key problems such as subjective diagnosis, experiential treatment, and poor overall prognosis are still challenging. In recent years, some exciting discoveries have been made in the research on objective biomarkers of SCH, mainly focusing on genetic susceptibility genes, metabolic indicators, immune indices, brain imaging, electrophysiological characteristics. This review aims to summarize the biomarkers that may be used for the prediction and diagnosis of SCH.
Bibliography:ObjectType-Article-2
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ISSN:2749-9642
2097-0773
2749-9642
DOI:10.1515/mr-2022-0009