Ophiobolin Sesterterpenoids and Pyrrolidine Alkaloids from the Sponge-Derived Fungus Aspergillus ustus

• Published in: Helvetica chimica acta Vol. 94; no. 4; pp. 623 - 631
• Main Authors: Liu, Hong-Bing, Edrada-Ebel, RuAngelie, Ebel, Rainer, Wang, Yao, Schulz, Barbara, Draeger, Siegfried, Müller, Werner E. G., Wray, Victor, Lin, Wen-Han, Proksch, Peter
• Format: Journal Article
• Language: English
• Published: Zürich WILEY-VCH Verlag 01.04.2011; WILEY‐VCH Verlag; Wiley
• Subjects: Alkaloids; Aspergillus ustus; Chemistry; Chemistry, Multidisciplinary; Cytotoxic activity; Fungi; Physical Sciences; Pyrrolidine alkaloids; Science & Technology; Sesterterpenoids; Suberites domuncula; MARINE; METABOLITES

Chemical examination of the fungus Aspergillus ustus isolated from the Mediterranean sponge Suberites domuncula yielded the five new ophiobolin‐type sesterterpenoids 1–5 and the two new pyrrolidine alkaloids 6 and 7, together with the known compound aurantiamine and cerebroside D. The structures of...