Is hypertension the fate of aortic coarctation patients treated with Cheatham Platinum (CP) stent?

• Published in: Journal of interventional cardiology Vol. 31; no. 2; pp. 244 - 250
• Main Authors: Baykan, Ali, Demiraldi, Ayse G., Tasci, Onur, Pamukcu, Ozge, Sunkak, Suleyman, Uzum, Kazım, Sezer, Sadettin, Narin, Nazmi
• Format: Journal Article
• Language: English
• Published: United States Hindawi Limited 01.04.2018
• Subjects: Adolescent; Aorta; aortic coarctation; Aortic Coarctation - complications; Aortic Coarctation - physiopathology; Aortic Coarctation - surgery; Arteriography; Blood pressure; blood pressure monitoring; Blood Pressure Monitoring, Ambulatory - methods; Blood Pressure Monitoring, Ambulatory - statistics & numerical data; Cardiovascular diseases; Cardiovascular Diseases - diagnosis; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - etiology; Cardiovascular system; Cheatham Platinum stent; Child; Echocardiography; Echocardiography - methods; Female; Heart diseases; Humans; Hypertension; Hypertension - diagnosis; Hypertension - epidemiology; Hypertension - etiology; Implants; Incidence; Male; Patients; Platinum; Platinum - therapeutic use; Pressure measurement; Pulse Wave Analysis; Risk Factors; Statistics as Topic; Stents; Turkey - epidemiology; Velocity; Ventricle; Cheatham Platinum stent; aortic coarctation; hypertension; echocardiography; blood pressure monitoring
• ISSN: 0896-4327; 1540-8183
• DOI: 10.1111/joic.12460

Aim The aim of this study is to address the presence of hypertension and risk for cardiovascular diseases in patients with Coarctation of the Aorta (CoA) who were treated with endovascular stent placement. Methods Twenty patients (mean age: 14.2 ± 3.9 years) who were treated with stent and 20 age‐ and sex‐matched controls were included to the study. Structure and functions of left ventricle were assessed by echocardiography. Carotid intima media (CIM) thickness was measured by using sonography as a marker for detecting cardiovascular risk. As indirect marker of arterial stiffness, pulse wave velocity, and augmentation index were recorded by ambulatory blood pressure monitorization/arteriography device. Results By ambulatory blood pressure monitorization, 24 h and daytime systolic and mean arterial pressure values were found to be significantly higher in patient group. Based on percentile values, 15% and 5% of patients were pre‐hypertensive and hypertensive, respectively. Pulse wave velocity and cardiac output values were found to be significantly higher than control group. CIM thickness was also found to be significantly higher in patient group when compared to controls. Conclusions It was shown that hypertension incidence as demonstrated by ambulatory blood pressure monitorization and risk for cardiovascular diseases as indicated by CIM thickness and Pulse wave velocity were higher than those in healthy population even after CoA is corrected.