Very Delayed Onset of Neurosarcoidosis After Isolated Optic Perineuritis

Without the characteristic imaging finding of optic nerve sheath enhancement, it may be difficult to distinguish clinically from optic neuritis as there is variable involvement of the optic nerve itself, causing visual field deficits and decreased central acuity.1 Primary disease may represent a loc...

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Bibliographic Details
Published inCanadian journal of neurological sciences Vol. 49; no. 2; pp. 305 - 307
Main Authors Donaldson, Laura, Provias, John, Carmona, Raj, Rodriguez, Amadeo R.
Format Journal Article
LanguageEnglish
Published New York, USA Cambridge University Press 01.03.2022
Subjects
Central Nervous System Diseases - complications
Central Nervous System Diseases - diagnostic imaging
Conflicts of interest
Edema
Glycoproteins
Granulomas
Humans
Letters to the Editor: Published Article
Lymphocytes
Optic nerve
Proteins
Sarcoidosis
Sarcoidosis - complications
Sarcoidosis - diagnostic imaging
Syphilis
Tuberculosis
Vein & artery diseases
Vision Disorders
Sarcoidosis
Perineuritis
Adalimumab
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Summary:Without the characteristic imaging finding of optic nerve sheath enhancement, it may be difficult to distinguish clinically from optic neuritis as there is variable involvement of the optic nerve itself, causing visual field deficits and decreased central acuity.1 Primary disease may represent a localized form of idiopathic orbital inflammation. Blood work showed normal erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and angiotensin converting enzyme (ACE), negative rheumatoid factor (RF), anti-nuclear antibodies (ANA) and anti-neutrophilic cytoplasmic autoantibody (ANCA), and normal protein electrophoresis complement and IgG4 levels. Conflict of Interest The authors have no conflicts of interest to declare.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0317-1671
2057-0155
DOI:10.1017/cjn.2021.61