Two New CPA-Type Indole Alkaloids from the Tobacco-Derived Fungus Aspergillus versicolor and the Anti-TMV Activity

Two new CPA-type indole alkaloids ( 1 and 2 ) were isolated from the fungus Aspergillus versicolor. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The res...

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Published inChemistry of natural compounds Vol. 58; no. 5; pp. 888 - 891
Main Authors Wang, Hua-Shun, Zhang, Ling-Fang, Liu, Ming-Xin, Gu, Xue-jiao, Li, Man-fei, Zheng, Chao-Pei, Wang, Kai, Xiao, Dong, Zhou, Min, Li, Xue-Mei, Hu, Qiu-Fen, Li, Yin-Ke
Format Journal Article
LanguageEnglish
Published New York Springer US 01.09.2022
Springer Nature
Springer
Springer Nature B.V
Subjects
Accountants
Alkaloids
Chemistry
Chemistry and Materials Science
Chemistry, Medicinal
Chemistry, Organic
Chemistry/Food Science
Fungi
Life Sciences & Biomedicine
NMR
Nuclear magnetic resonance
Organic Chemistry
Pharmacology & Pharmacy
Physical Sciences
Plant Sciences
Science & Technology
Tobacco
anti-TMV activity
CPA-type indole alkaloids
Aspergillus versicolor
BIOACTIVE COMPOUNDS
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Summary:Two new CPA-type indole alkaloids ( 1 and 2 ) were isolated from the fungus Aspergillus versicolor. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 showed potential anti-TMV activity with inhibition rates of 33.6 and 29.4% respectively. These rates are close to that of positive control.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-022-03822-7