Atypical Teratoid Rhabdoid Tumor: A Possible Oriented Female Pathology?

Atypical teratoid rhabdoid tumor is a rare lesion that occurs mainly in children can be supratentorial or infratentorial and it accounts for 1-2% of pediatric brain tumors and over 10% of central nervous system (CNS) tumors in infants, with a male preponderance up to 3 years of age, more than 50% of...

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Published inFrontiers in oncology Vol. 12; p. 854437
Main Authors Baiano, Cinzia, Della Monica, Rosa, Franca, Raduan Ahmed, Del Basso De Caro, Maria Laura, Cavallo, Luigi Maria, Chiariotti, Lorenzo, Ius, Tamara, Jouanneau, Emmanuel, Somma, Teresa
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 01.04.2022
Subjects
endoscopic endonasal surgery
hystopathological features
molecular biology
multimodal approach
Oncology
sellar ATRT
molecular biology
sellar ATRT
endoscopic endonasal surgery
hystopathological features
multimodal approach
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Summary:Atypical teratoid rhabdoid tumor is a rare lesion that occurs mainly in children can be supratentorial or infratentorial and it accounts for 1-2% of pediatric brain tumors and over 10% of central nervous system (CNS) tumors in infants, with a male preponderance up to 3 years of age, more than 50% of these occur in the cerebellum. In this report we describe four new cases of sellar AT/RTs underwent endoscopic endonasal approach and different adjuvant therapies. Our aim is to report the clinical, radiological and pathological features of these rare lesions, focusing on the possibility to perform an early diagnosis and appropriate therapeutic strategy.
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Edited by: Maria Caffo, University of Messina, Italy
This article was submitted to Neuro-Oncology and Neurosurgical Oncology, a section of the journal Frontiers in Oncology
Reviewed by: Pawel Buczkowicz, PhenoTips, Canada; Ji Hoon Phi, Seoul National University Children’s Hospital, South Korea
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2022.854437