Antimicrobial activities of 2,6-dimethoxy-1,4-benzoquinone and its structurally related analogues against seven food-borne bacteria

• Published in: Applied biological chemistry Vol. 57; no. 6; pp. 699 - 701
• Main Authors: Park, Jun-Hwan, Shim, Kwan Seob, Lee, Hoi-Seon
• Format: Journal Article
• Language: English
• Published: Seoul The Korean Society for Applied Biological Chemistry 01.12.2014; Springer Nature B.V; 한국응용생명화학회
• Subjects: Antiinfectives and antibacterials; Antimicrobial activity; Antimicrobial agents; Applied Microbiology; Bacteria; Benzoquinone; Biological Techniques; Bioorganic Chemistry; Chemistry; Chemistry and Materials Science; Food; Food sources; Listeria; Listeria monocytogenes; 농학; food-borne bacteria; structural analogues; antimicrobial activity; 2,6-dimethoxy-1,4-benzoquinone
• ISSN: 1738-2203; 2468-0834; 2234-344X; 2468-0842
• DOI: 10.1007/s13765-014-4252-4

Antimicrobial activities of 2,6-dimethoxy-1,4-benzoquinone and its structurally related analogues (2,6-dichloro-, 2,6-dimethyl-, 2,5-dichloro-, and 2,5-dimethyl-) were evaluated at 0.5 mg/disc against seven food-borne bacteria. 2,6-Dimethoxy-1,4-benzoquinone showed antimicrobial activity against Staphylococcus intermedius (22.0 mm), Staphlococcus epidermidis (19.5 mm), Shigella sonnei (16.0 mm), and Listeria monocytogenes (15.0 mm). Furthermore, these structural analogues exhibited antimicrobial activity against all tested food-borne bacteria except 2,6-dichloro-1,4-benzoquinone. In conclusion, 2,6-dimethoxy-1,4-benzoquinone and its structural analogues are useful as a source of food supplemental agents.