Cardiovascular risk factors, monitoring, and therapy for HIV-infected patients

Cardiovascular complications are important contributors to morbidity and mortality in HIV-infected patients. These complications can usually be detected at subclinical levels with monitoring, which can help guide targeted interventions. This article reviews available data on types and frequency of c...

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Published inAIDS (London) Vol. 17 Suppl 1; pp. S96 - S122
Main Authors Lipshultz, Steven E, Fisher, Stacy D, Lai, Wyman W, Miller, Tracie L
Format Journal Article
LanguageEnglish
Published England 01.04.2003
Subjects
AIDS/HIV
Anti-Infective Agents - therapeutic use
Biomarkers - blood
Biopsy
Cardiac Catheterization
Cardiovascular Diseases - diagnosis
Cardiovascular Diseases - therapy
Cardiovascular Diseases - virology
Coronary Disease - prevention & control
Coronary Disease - virology
Cytokines - antagonists & inhibitors
Echocardiography
Echocardiography, Stress
Electrocardiography, Ambulatory
Genetic Testing
Heart Diseases - diagnosis
Heart Diseases - therapy
Heart Diseases - virology
HIV Infections - complications
Humans
Lipids - blood
Physical Examination
Risk Assessment
Tomography, X-Ray Computed
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Summary:Cardiovascular complications are important contributors to morbidity and mortality in HIV-infected patients. These complications can usually be detected at subclinical levels with monitoring, which can help guide targeted interventions. This article reviews available data on types and frequency of cardiovascular manifestations in HIV-infected patients and proposes monitoring strategies aimed at early subclinical detection. In particular, we recommend routine echocardiography for HIV-infected patients, even those with no evidence of cardiovascular disease. We also review preventive and therapeutic cardiovascular interventions. For procedures that have not been studied in HIV-infected patients, we extrapolate from evidence-based guidelines for the general population.
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ISSN:0269-9370
DOI:10.1097/00002030-200304001-00014