Axis formation and patterning in zebrafish

A large collection of mutations affecting zebrafish embryogenesis was described in 1996. The cloning of the affected genes has now provided novel insights into the role and regulation of signaling by BMP, Nodal, Wnt, FGF, Hedgehog, Delta, Slit, retinoic acid and lipids. Detailed analyses have reveal...

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Bibliographic Details
Published inCurrent Opinion in Genetics & Development Vol. 11; no. 4; pp. 393 - 404
Main Author Schier, Alexander F
Format Book Review Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.08.2001
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Summary:A large collection of mutations affecting zebrafish embryogenesis was described in 1996. The cloning of the affected genes has now provided novel insights into the role and regulation of signaling by BMP, Nodal, Wnt, FGF, Hedgehog, Delta, Slit, retinoic acid and lipids. Detailed analyses have revealed a complex genetic network that patterns the early embryo.
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ISSN:0959-437X
1879-0380
DOI:10.1016/S0959-437X(00)00209-4