Effect of the Pericardium on Left Ventricular Volume and Function in Acute Hypervolaemia

The effect of acute volume overload was studied in 20 dogs, nine of which had undergone pericardiectomy. End-diastolic and end-systolic left ventricular volumes, as determined by biplane angiocardiography, were significantly higher, and the ejected fraction relatively lower in the pericardiectomized...

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Bibliographic Details
Published inCardiovascular research Vol. 2; no. 3; pp. 284 - 289
Main Authors Bartle, Stuart H., Hermann, Hector J., Cavo, John W., Moore, Rick A., Costenbader, J. Markel
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.07.1968
Subjects
Angiocardiography
Animals
Aorta
Blood Pressure
Blood Volume
Cardiac Output - physiology
Dilatation
Dogs
Heart Rate
Heart Ventricles - drug effects
Isotonic Solutions - pharmacology
Mitral Valve Insufficiency - chemically induced
Pericardium - physiology
Pulmonary Artery
Ventricular Function
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Summary:The effect of acute volume overload was studied in 20 dogs, nine of which had undergone pericardiectomy. End-diastolic and end-systolic left ventricular volumes, as determined by biplane angiocardiography, were significantly higher, and the ejected fraction relatively lower in the pericardiectomized group. It is concluded that the pericardium prevents excessive left ventricular dilatation and impairment of the ventricular function during acute hypervolaemia.
Bibliography:istex:19ACB6B0CCC92F8BDF8BD4F0618E1302A88AE7A0
This investigation was supported in part by Public Health Research Grant HE-08938 from the National Heart Institute, and by Public Health Service Training Grants 5T05-GM 01613-9 and HE-5418.
ark:/67375/HXZ-1NQLF481-8
ArticleID:2-3-284
ISSN:0008-6363
1755-3245
DOI:10.1093/cvr/2.3.284