The Movement Disorders task force review of dysautonomia rating scales in Parkinson's disease with regard to symptoms of orthostatic hypotension

• Published in: Movement disorders Vol. 26; no. 11; pp. 1985 - 1992
• Main Authors: Pavy-Le Traon, Anne, Amarenco, Gerard, Duerr, Susanne, Kaufmann, Horacio, Lahrmann, Heinz, Shaftman, Stephanie R., Tison, François, Wenning, Gregor K., Goetz, Christopher G., Poewe, Werner, Sampaio, Cristina, Schrag, Anette, Stebbins, Glenn T., Rascol, Olivier
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.09.2011; Wiley
• Subjects: Advisory Committees - standards; autonomic failure; Biological and medical sciences; clinimetrics; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Humans; Hypotension, Orthostatic - etiology; Medical sciences; Neurology; orthostatic hypotension; orthostatic symptoms; Parkinson Disease - complications; Parkinson Disease - diagnosis; Parkinson's disease; PubMed - statistics & numerical data; rating scales; Reproducibility of Results; Severity of Illness Index; Surveys and Questionnaires; clinimetrics; orthostatic hypotension; Nervous system diseases; Parkinson's disease; rating scales; Force; Parkinson disease; autonomic failure; Cardiovascular disease; Cerebral disorder; Postural hypotension; orthostatic symptoms; Arterial hypotension; Central nervous system disease; Diseases of the autonomic nervous system; Degenerative disease; Extrapyramidal syndrome
• ISSN: 0885-3185; 1531-8257
• DOI: 10.1002/mds.23742

Orthostatic hypotension is defined as a blood pressure fall of > 20 mm Hg systolic and/or 10 mm Hg diastolic within 3 minutes of an upright position. The Movement Disorders Society commissioned a task force to assess existing clinical rating scales addressing symptoms of orthostatic hypotension in Parkinson's disease. Seven neurologists and a clinimetrician assessed each scale's previous use and critiqued its clinimetric properties. A scale was “recommended” if it had been applied to populations of patients with Parkinson's disease, with data on its use in studies beyond the group that developed the scale, and was found to be clinimetrically valid. A scale was considered “suggested” if it had been applied to Parkinson's disease, but only 1 of the other criteria was applied. A scale was “listed” if it met only 1 criterion. Symptoms of orthostatic hypotension are generally assessed in scales on wider autonomic or nonmotor symptoms. Some scales designed to detect orthostatic hypotension–related symptoms provide information on their severity: the AUTonomic SCale for Outcomes in PArkinson's Disease and the COMPosite Autonomic Symptom Scale met criteria for recommended with some limitations; the Novel Non‐Motor Symptoms Scale and the Orthostatic Grading Scale were classified as suggested. The Self‐completed Non‐Motor Symptoms Questionnaire for Parkinson's Disease was classified as suggested as a tool for screening orthostatic symptoms. However, these and the listed scales need further validation and application before they can be recommended for clinical use in patients with Parkinson's disease. © 2011 Movement Disorder Society