Effect of PD fluid instillation on the peritonitis‐induced influx and bacterial clearing capacity of peritoneal cells

• Published in: Nephrology, dialysis, transplantation Vol. 16; no. 3; pp. 679 - 682
• Main Authors: Hekking, Liesbeth H. P., Huijsmans, Agnes, Van Gelderop, Erwin, Wieslander, Andes P., Havenith, Carin E. G., van den Born, Jacob, Beelen, Robert H. J.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Oxford Oxford University Press 01.03.2001
• Subjects: Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Animals; Bacteria - immunology; Biological and medical sciences; Dialysis Solutions - pharmacology; Emergency and intensive care: renal failure. Dialysis management; Epithelium - drug effects; Epithelium - immunology; Epithelium - pathology; Intensive care medicine; Male; Medical sciences; mesothelial cells; Peritoneal Dialysis; peritoneal dialysis fluid; peritoneal immune defence; Peritoneum - drug effects; Peritoneum - immunology; Peritoneum - pathology; Peritonitis - immunology; Peritonitis - microbiology; rat model; Rats; Rats, Wistar; Extrarenal dialysis; Animal model; Vertebrata; Mammalia; Rat; Animal; Rodentia; Dialysis fluid; Glucose; Peritoneal dialysis; Comparative study

Background. The commonly used peritoneal dialysis fluids contain glucose as the osmotic agent. Heat sterilization leads to the formation of glucose degradation products which contribute, together with glucose, to the formation of advanced glycation end‐products (AGEs). AGEs have been shown to be pre...