A preliminary Monte Carlo study for the treatment head of a carbon-ion radiotherapy facility using TOPAS

• Published in: EPJ Web of Conferences Vol. 153; p. 4018
• Main Authors: Liu, Hongdong, Zhang, Lian, Chen, Zhi, Liu, Xinguo, Dai, Zhongying, Li, Qiang, Xu, Xie George
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Les Ulis EDP Sciences 01.01.2017
• Subjects: Carbon; Computer simulation; Design optimization; Feasibility studies; Monte Carlo simulation; Physics; Radiation therapy
• ISSN: 2100-014X; 2101-6275; 2100-014X
• DOI: 10.1051/epjconf/201715304018

In medical physics it is desirable to have a Monte Carlo code that is less complex, reliable yet flexible for dose verification, optimization, and component design. TOPAS is a newly developed Monte Carlo simulation tool which combines extensive radiation physics libraries available in Geant4 code, easyto-use geometry and support for visualization. Although TOPAS has been widely tested and verified in simulations of proton therapy, there has been no reported application for carbon ion therapy. To evaluate the feasibility and accuracy of TOPAS simulations for carbon ion therapy, a licensed TOPAS code (version 3_0_p1) was used to carry out a dosimetric study of therapeutic carbon ions. Results of depth dose profile based on different physics models have been obtained and compared with the measurements. It is found that the G4QMD model is at least as accurate as the TOPAS default BIC physics model for carbon ions, but when the energy is increased to relatively high levels such as 400 MeV/u, the G4QMD model shows preferable performance. Also, simulations of special components used in the treatment head at the Institute of Modern Physics facility was conducted to investigate the Spread-Out dose distribution in water. The physical dose in water of SOBP was found to be consistent with the aim of the 6 cm ridge filter.