Managing Arrhythmias before and after Aortic Valve Surgery in Children

• Published in: American journal of cardiovascular drugs : drugs, devices, and other interventions Vol. 12; no. 1; pp. 23 - 34
• Main Authors: Kandlikar Patel, Jyoti, Ramesh Iyer, V.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.02.2012; Springer Nature B.V
• Subjects: Aortic Valve - pathology; Aortic Valve - surgery; Arrhythmias, Cardiac - etiology; Arrhythmias, Cardiac - physiopathology; Arrhythmias, Cardiac - therapy; Cardiology; Child; Disease Management; Heart Valve Diseases - physiopathology; Heart Valve Diseases - surgery; Heart Valve Prosthesis Implantation - adverse effects; Humans; Incidence; Medicine; Medicine & Public Health; Pharmacology/Toxicology; Pharmacotherapy; Postoperative Complications - etiology; Postoperative Complications - physiopathology; Postoperative Complications - therapy; Review Article; Aortic Valve Replacement; Ventricular Arrhythmia; Aortic Stenosis; Aortic Valve; Ventricular Tachycardia
• ISSN: 1175-3277; 1179-187X
• DOI: 10.2165/11596350-000000000-00000

The proximity of the coronary arteries and the bundle of His to the aortic valve may contribute to the pathogenesis of arrhythmias in patients with aortic valve disease. Severe aortic valve disease may also adversely alter left ventricular hemodynamics (end-diastolic dimensions and wall stress) and thus create a substrate for ventricular arrhythmias before any intervention is performed. The severity of these arrhythmias depends on the severity of the underlying substrate (or the specific problem, such as aortic stenosis or aortic regurgitation), the age at which the aortic valve intervention was performed, the type of intervention (i.e. transcatheter aortic valve interventions or open aortic valve replacement or repair), and the reversibility of the altered hemodynamics after surgery. Both bradyarrhythmias and tachyarrhythmias are known complications of aortic valve interventions. Although data are scant, this review summarizes the incidence of arrhythmias before and after aortic valve interventions from a pediatric perspective.