Case report of a 65-year-old man with biatrial metastatic localisation from poorly differentiated cutaneous squamous cell carcinoma

We report the case of an immunocompetent 65-year-old man affected by cutaneous squamous cell carcinoma (cSCC) with lung and biatrial metastatic localisation. In May 2018, the patient underwent lower limb amputation due to the finding of a large ulceration which upon biopsy was found to be a poorly d...

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Bibliographic Details
Published inEcancermedicalscience Vol. 13; p. 977
Main Authors Dottorini, Lorenzo, Sarno, Italo, Scopelliti, Pasquale, Cotroneo, Gianluca, Duluc, Maribel, Iaculli, Alessandro, Giuntini, Nicola, Brena, Federica, Nastasi, Giuseppe
Format Journal Article
LanguageEnglish
Published England Cancer Intelligence 19.11.2019
Subjects
Case Report
Case reports
Localization
Metastasis
Patients
Skin cancer
Squamous cell carcinoma
Transplants & implants
Tumors
Italy
cutaneous
biatrial
carcinoma
atrial metastases
skin
cancer
heart
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Summary:We report the case of an immunocompetent 65-year-old man affected by cutaneous squamous cell carcinoma (cSCC) with lung and biatrial metastatic localisation. In May 2018, the patient underwent lower limb amputation due to the finding of a large ulceration which upon biopsy was found to be a poorly differentiated squamous cell carcinoma (SCC), ulcerated, full-thickness infiltrating from the skin to the underlying bone tissue. After 1 month, a radiological restaging found multiple pulmonary localisations and a right-atrial metastatic localisation. The patient was then studied in-depth and a transesophageal echocardiogram found that the patient had two 2 and 5 cm metastatic localisations in the left atrium and a 3-cm metastatic localisation in the right atrium. Informed about the clinical situation and about the risks of a chemotherapeutic treatment, the patient decided not to start any treatment. This case represents, to our knowledge, the only case of a biatrial metastatic localisation from cSCC and is representative of how cardiac symptoms and signs in patients affected by this disease must be evaluated.
ISSN:1754-6605
1754-6605
DOI:10.3332/ecancer.2019.977