Combined radiofrequency-surgical debulking of advanced abdomino-pelvic tumors

Advanced abdomino-pelvic tumors are often unresectable using surgery alone. The current study evaluated a combination of radiofrequency (RF) ablation (RFA) and surgical debulking for such lesions. Between July 2003 and November 2004, we treated 16 patients. Fourteen had either pelvic side wall (n =...

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Published inThe American journal of surgery Vol. 192; no. 6; pp. 833 - 836
Main Authors Pearlman, Nathan W., McCarter, Martin D., Escober, Guillermo, MacDermott, Tracey
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.12.2006
Elsevier Limited
Subjects
Abdomen
Abdominal Neoplasms - mortality
Abdominal Neoplasms - pathology
Abdominal Neoplasms - therapy
Abdomino-pelvic tumors
Adult
Aged
Aged, 80 and over
Cancer
Cancer therapies
Catheter Ablation
Chemotherapy
Combined Modality Therapy
Failure
Female
Humans
Male
Middle Aged
Neoplasm Staging
Pain
Patients
Pelvic Neoplasms - mortality
Pelvic Neoplasms - pathology
Pelvic Neoplasms - therapy
Radiofrequency ablation
Success
Surgery
Surgical debulking
Surgical Procedures, Operative
Survival Analysis
Tumors
Vertebrae
Radiofrequency ablation
Surgical debulking
Abdomino-pelvic tumors
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Summary:Advanced abdomino-pelvic tumors are often unresectable using surgery alone. The current study evaluated a combination of radiofrequency (RF) ablation (RFA) and surgical debulking for such lesions. Between July 2003 and November 2004, we treated 16 patients. Fourteen had either pelvic side wall (n = 8), sacro-iliac joint (n = 4), or vertebral (n = 2) fixation. One tumor engulfed root of mesentery, the last involved stomach-liver-vena. All patients had received prior treatment. The RF probe was placed in the center of the tumor, a 4- to 6-cm tissue core ablated, and the core curetted out or aspirated. This was repeated centrifugally out to the tumor capsule. Control of the target lesion for more than 6 months was achieved in 10 (62%) patients; 2 died within 3 months, and 4 had tumor progression in less than 6 months. Median survival is 18+ months. Combined RFA–surgical debulking was feasible and beneficial in 62%% of patients with otherwise inoperable abdomino-pelvic tumors.
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ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2006.08.053