Vesicovaginal Fistula Associated with Cytomegalovirus Infection in an HIV-Infected Patient

Background: Cytomegalovirus (CMV) can cause multisystem disease in human immunodeficiency virus (HIV)-infected patients. An association with a vesicovaginal fistula has not previously been reported. Case: An HIV-infected African-American female presented with back pain, swelling and paralysis of her...

Full description

Saved in:
Bibliographic Details
Published inGynecologic and obstetric investigation Vol. 63; no. 3; pp. 143 - 145
Main Authors Awonuga, Awoniyi, Greenbaum, Laura, Merhi, Zaher, Levgur, Michael, Minkoff, Howard
Format Journal Article
LanguageEnglish
Published Basel, Switzerland Karger 01.01.2007
S. Karger AG
Subjects
Adult
AIDS-Related Opportunistic Infections - complications
AIDS-Related Opportunistic Infections - immunology
Biological and medical sciences
Case Report
Cytomegalovirus
Cytomegalovirus Infections - complications
Disease Progression
Female
Gynecology. Andrology. Obstetrics
HIV Infections - complications
HIV Infections - immunology
Human cytomegalovirus
Human immunodeficiency virus
Human viral diseases
Humans
Infectious diseases
Medical sciences
Vesicovaginal Fistula - diagnosis
Vesicovaginal Fistula - pathology
Vesicovaginal Fistula - surgery
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Vesicovaginal fistula
Cytomegalovirus
Human immunodeficiency virus
Human
Immunopathology
Herpesviridae
Gynecology
Retroviridae
AIDS
Fistula
Vesicovaginal
Betaherpesvirinae
Immune deficiency
Lentivirus
Obstetrics
Infection
Virus
Viral disease
Online AccessGet full text

Cover

More Information
Summary:Background: Cytomegalovirus (CMV) can cause multisystem disease in human immunodeficiency virus (HIV)-infected patients. An association with a vesicovaginal fistula has not previously been reported. Case: An HIV-infected African-American female presented with back pain, swelling and paralysis of her lower extremities and continuous leakage of urine. Fundoscopic examination was typical of CMV retinitis. Doppler and CT studies showed bilateral deep vein thrombosis and bilateral pulmonary emboli, respectively. Anticoagulant therapy was started, and a Greenfield filter was placed. An examination under anesthesia and cystoscopy showed extensive vulvar and rectal condylomata, a large, necrotic, anterior vaginal mass, and a large vesicovaginal fistula. All necrotic tissue was resected and the biopsies taken identified CMV cytopathic effect. Conclusion: Vesicovaginal fistula in an immunocompromised individual may be a local manifestation of systemic CMV disease.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Case Study-2
ObjectType-Feature-4
ObjectType-Report-1
ObjectType-Article-3
ISSN:0378-7346
1423-002X
DOI:10.1159/000096475