Advances in three-dimensional nanofibrous macrostructures via electrospinning

• Published in: Progress in polymer science Vol. 39; no. 5; pp. 862 - 890
• Main Authors: Sun, B., Long, Y.Z., Zhang, H.D., Li, M.M., Duvail, J.L., Jiang, X.Y., Yin, H.L.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.05.2014; Elsevier
• Subjects: 3D nanofibrous macrostructures; Applied sciences; Biological and medical sciences; Electrospinning; Energy harvesting and storage; Exact sciences and technology; Filtration; Machinery and processing; Medical sciences; Plastics; Polymer industry, paints, wood; Spinning; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Technology of polymers; Technology. Biomaterials. Equipments; Tissue engineering; TCP; DPMD; PS; PLA; EDC; PU; Electrospinning; PVP; MTT; 2D; SF; PLLA; PLAGA; HAp; PPV; HUVEC; 3D nanofibrous macrostructures; μCT; Filtration; Tissue engineering; PHBV; PGA; GAG; ECM; RGD; PEUU; 3D; Energy harvesting and storage; PLLCL; 1D; PLGA; PCL; PAMPS; PVA; PEO; PAN; DSSC; State of the art; Nanofiber; Polymer; Property processing relationship; Structure processing relationship; Three dimensional structure; Morphology; Biomaterial; Manufacturing
• ISSN: 0079-6700; 1873-1619
• DOI: 10.1016/j.progpolymsci.2013.06.002

Compared with other nanofiber fabrication processes, electrospinning is versatile and superior in production and construction of ordered or more complex nanofibrous assemblies. Besides traditional two-dimensional (2D) nanofibrous structures, electrospinning is powerful in fabrication of three-dimensional (3D) fibrous macrostructures, especially for tissue engineering applications. This article summarizes and reviews recent advances in various promising and cutting-edge electrospinning techniques, including multilayering electrospinning, post-processing after electrospinning, liquid-assisted collection, template-assisted collection, porogen-added electrospinning, and self-assembly. And their formation mechanisms, features, and the challenges of electrospinning have also been discussed. Furthermore, these 3D nanofibrous macrostructures have been demonstrated to have potential applications in tissue engineering, energy harvesting and storage, and filtration.