Serum copper and zinc concentrations in serum from patients with cancer and cardiovascular disease

• Published in: The Science of the total environment Vol. 204; no. 1; pp. 27 - 35
• Main Authors: Martín-Lagos, F., Navarro-Alarcón, M., Terrés-Martos, C., López-G de la Serrana, H., López-Martínez, M.C.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 19.09.1997
• Subjects: Adult; Aged; Aging; Cancer; Cardiomyopathies - blood; Cardiopathy; Copper; Copper - blood; Cross-Sectional Studies; Digestive System Neoplasms - blood; Female; Genital Neoplasms, Female - blood; Genital Neoplasms, Male - blood; Hematologic Neoplasms - blood; Humans; Male; Middle Aged; Myocardial Ischemia - blood; Neoplasms - blood; Respiratory Tract Neoplasms - blood; Serum; Sex Factors; Zinc; Zinc - blood; Serum; Cardiopathy; Copper; Zinc; Cancer
• ISSN: 0048-9697; 1879-1026
• DOI: 10.1016/S0048-9697(97)00163-0

A single cross-sectional study for serum copper and zinc levels was evaluated in 20 patients with cancer (respiratory, digestive, haematological, gynaecological) and 21 patients with cardiopathy (acute myocardial infarction and ischemic cardiomyopathy). A control group of 84 healthy subjects was selected. The mean serum zinc levels in patients with gynaecological cancer and ischemic cardiomyopathy were significantly lower than the control group ( P < 0.05). However, the mean serum copper level was not statistically different among patients with cancer ( P > 0.05) and cardiomyopathy ( P > 0.05) than the control group. Male patients did not have statistically different values for serum Cu ( P > 0.05) and Zn ( P > 0.05) than those found in female patients. Patients' age did not have any statistical influence ( P > 0.05) on serum Cu and Zn levels.