Salivary gland development

Salivary glands provide an excellent model for the study of epithelial–mesenchymal interactions and branching morphogenesis. This review will discuss the anatomy of different types of glands, in a range of different organisms. Then, concentrating on the mouse submandibular gland, the stages of saliv...

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Bibliographic Details
Published inSeminars in cell & developmental biology Vol. 18; no. 2; pp. 237 - 244
Main Author Tucker, A.S.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.04.2007
Subjects
Animals
Branching morphogenesis
Epithelial–mesenchymal interactions
Epithelium - embryology
Epithelium - physiology
Mesoderm - cytology
Mesoderm - physiology
Mice
Models, Biological
Morphogenesis
Organogenesis
Salivary gland
Salivary Glands - cytology
Salivary Glands - embryology
Branching morphogenesis
Salivary gland
Epithelial–mesenchymal interactions
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Summary:Salivary glands provide an excellent model for the study of epithelial–mesenchymal interactions and branching morphogenesis. This review will discuss the anatomy of different types of glands, in a range of different organisms. Then, concentrating on the mouse submandibular gland, the stages of salivary gland development will be reviewed and the relative role of the mesenchyme and the epithelium will be discussed. Finally, the genes thought to play a role in development of the glands from initiation to differentiation will be reviewed.
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ISSN:1084-9521
1096-3634
DOI:10.1016/j.semcdb.2007.01.006