Mulinane-type diterpenoids from Mulinum spinosum

• Published in: Phytochemistry (Oxford) Vol. 63; no. 8; pp. 883 - 886
• Main Authors: Chiaramello, Alejandra I., Ardanaz, Carlos E., Garcı́a, Eduardo E., Rossomando, Pedro C.
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 01.08.2003; Elsevier
• Subjects: Apiaceae; Apiaceae - chemistry; Biochemistry & Molecular Biology; Biological and medical sciences; Chemical constitution; Diterpenes - chemistry; Diterpenes - isolation & purification; Diterpenoid; Fundamental and applied biological sciences. Psychology; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; Molecular Structure; Mulin-11-ene-13-α,14-α-dihydroxy-20-oic acid; Mulin-12-ene-14-one-20-oic acid; Mulinane derivatives; Mulinum spinosum; Plant Components, Aerial - chemistry; Plant physiology and development; Plant Sciences; Plants, Medicinal - chemistry; Science & Technology; Mulin-12-ene-14-one-20-oic acid; Mulinum spinosum; Diterpenoid; Apiaceae; Mulinane derivatives; Mulin-11-ene-13-α,14-α-dihydroxy-20-oic acid; ACID; mulinane derivatives; mulin-12-ene-14-one-20-oic acid; CRASSIFOLIUM; diterpenoid; mulin-11-ene-13-alpha,14-alpha-dihydroxy-20-oic acid; Terpenoid; Molecular structure; Mulin-12-ene-14-one- 20-oic acid; Dicotyledones; Angiospermae; Diterpene; Above ground plant part; Spermatophyta; Umbelliferae
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/S0031-9422(03)00344-3

In addition to the known mulinolic and mulinenic acids, two diterpenoids, mulin-11-ene-13-α,14-α-dihydroxy-20-oic and mulin-12-ene-14-one-20-oic acids, were isolated from the aerial parts of Mulinum spinosum (Cav.) Pers. (Apiaceae). Their structures were determined based on spectroscopic studies. The isolation of mulin-11-ene-13-α, 14-α-dihydroxy-20-oic ( 1) and mulin-12-ene-14-one-20-oic ( 2) acids from M. spinosum is reported.