Peripheral Giant Cell Granuloma in Pregnancy: A Case Report

Peripheral giant cell granuloma (PGCG) is an asymptomatic, non-neoplastic, and proliferative lesion of unknown etiology. Possible pre-disposing factors, such as hormonal changes during pregnancy, have been suggested. However, the association between PGCG and pregnancy is controversial. There are few...

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Bibliographic Details
Published inApplied sciences Vol. 13; no. 23; p. 12688
Main Authors Alcaraz Baturoni, Francisco Javier, Zepeda Nuño, José Sergio, Nolasco González, Brenda Fernanda, Ramos Solano, Moisés, Martínez Nieto, Melissa, Lomelí Martínez, Sarah Monserrat
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.11.2023
Subjects
case report
Case reports
Cytokines
Dental calculus
Dental care
Development and progression
Edentulous
Etiology
giant-cell epulis
giant-cell hyperplasia
Granuloma
Granulomas
Hormones
International organizations
Jaw
Ligaments
Pathology
Patient compliance
peripheral giant-cell granuloma
Physiology
Pregnancy
Pregnant women
Trauma
Mexico
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Summary:Peripheral giant cell granuloma (PGCG) is an asymptomatic, non-neoplastic, and proliferative lesion of unknown etiology. Possible pre-disposing factors, such as hormonal changes during pregnancy, have been suggested. However, the association between PGCG and pregnancy is controversial. There are few reported clinical cases of pregnancy-associated PGCG in the literature, and they occurred only in the lower jaw. The present report is on a 35-year-old female patient at 36 weeks of gestation who presented with a PGCG in the central and lateral incisors of the upper jaw. Management consisted of complete surgical excision of the lesion along with a margin of healthy tissue under local anesthesia, followed by curettage of the adjacent fibers of the affected bony wall. The patient experienced adequate healing without complications. The diagnosis of PGCG was based on clinical characteristics, imaging examinations, and histopathological confirmation. The patient underwent postoperative follow-up evaluations at 3, 6, and 12 months, and there were no signs of recurrence.
ISSN:2076-3417
2076-3417
DOI:10.3390/app132312688