The Early History of the Neuroscience of Attention-Deficit/Hyperactivity Disorder

Research on the neurobiology and pharmacotherapy of attention-deficit/hyperactivity disorder (ADHD) has grown exponentially since 1980. A reasonable question is whether this research has improved our understanding and treatment of ADHD. This article describes relevant developments that took place ro...

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Bibliographic Details
Published inJournal of the history of the neurosciences Vol. 21; no. 3; pp. 263 - 279
Main Authors Baumeister, Alan A., Henderson, Kristopher, Pow, Joni Lee, Advokat, Claire
Format Journal Article
LanguageEnglish
Published England Taylor & Francis Group 01.07.2012
Taylor & Francis Ltd
Subjects
Alexander Crichton
amphetamine
Amphetamine - history
Amphetamine - therapeutic use
Attention Deficit Disorder with Hyperactivity - diagnosis
Attention Deficit Disorder with Hyperactivity - drug therapy
Attention Deficit Disorder with Hyperactivity - history
Attention deficit hyperactivity disorder
Bradley
Central Nervous System Stimulants - history
Central Nervous System Stimulants - therapeutic use
Charles Bradley
Child
Children & youth
Conan Kornetsky
Crichton
encephalitis lethargic
George Still
History of medicine and histology
History, 20th Century
Humans
Hyperactivity
hyperkinetic reaction of childhood
Kornetsky
methylphenidate
Methylphenidate - history
Methylphenidate - therapeutic use
Neurobiology - history
Neurosciences
organic driveness
Still
United States
United States
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Summary:Research on the neurobiology and pharmacotherapy of attention-deficit/hyperactivity disorder (ADHD) has grown exponentially since 1980. A reasonable question is whether this research has improved our understanding and treatment of ADHD. This article describes relevant developments that took place roughly between 1900 and 1970. During this time, the efficacy of stimulant therapy for the disorder was established and the symptoms of ADHD were linked to many possible nervous system disorders including in the brain-stem, reticular formation, diencephalon, basal ganglia, frontal lobes, and cortex. In 1970, the catecholamine hypothesis of ADHD was proposed. It is concluded that early theories about the neurobiologic basis of ADHD anticipated core ideas of modern theory.
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ISSN:0964-704X
1744-5213
DOI:10.1080/0964704X.2011.595649