Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020

Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the...

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Published inEmerging infectious diseases Vol. 27; no. 7; pp. 1953 - 1957
Main Authors Mohan, Teena, Nguyen, Ha T., Kniss, Krista, Mishin, Vasiliy P., Merced-Morales, Angiezel A., Laplante, Jennifer, St. George, Kirsten, Blevins, Patricia, Chesnokov, Anton, De La Cruz, Juan A., Kondor, Rebecca, Wentworth, David E., Gubareva, Larisa V.
Format Journal Article
LanguageEnglish
Published Atlanta Centers for Disease Control and Prevention 01.07.2021
Subjects
antigenic drift
Antimicrobial agents
Antiviral drugs
COVID-19
Disease control
Disease transmission
Dispatch
Drug resistance
Genomes
Global health
Health surveillance
influenza
influenza A(H1N1)
Medical laboratories
Mutation
neuraminidase inhibitor
Pandemics
Phylogenetics
Public health
Respiratory diseases
Seasons
Swine flu
transmission
Vaccines
Virology
Viruses
United States > US
Texas
Webb County Texas
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Summary:Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1080-6040
1080-6059
DOI:10.3201/eid2707.204593